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You Don’t Have to Take On
NASH Alone

An Exceptional Opportunity: The Symmetry Study

NASH is a common form of liver disease caused by fat cells stored in the liver, and accompanied by inflammation and liver cell damage. Over time, NASH can cause liver fibrosis (scarring) and may lead to cirrhosis or liver cancer. The Symmetry study (AK-US-001-0103) is researching an investigational drug called efruxifermin (EFX) to determine if it can reverse liver damage in people with compensated cirrhosis due to NASH. And if you are 18 to 75 years of age and have been diagnosed with NASH, you may qualify to participate.

EFX is designed to target compensated cirrhosis due to NASH by reducing liver fat, inflammation, and scarring. The purpose of the Symmetry study is to evaluate the safety and effectiveness of this investigational drug versus placebo in patients with NASH. “Investigational” means that this drug has not yet been FDA approved and its use is being allowed for research purposes only.

If you qualify for the Symmetry study and choose to participate, you will be enrolled for approximately 24 months, during which you’ll be randomly assigned to receive either EFX or placebo. A placebo looks just like the investigational drug but contains no active medication. Neither you nor the study doctor will know which you are receiving until the end of the study, but in the case of an emergency, the study doctor can quickly find out.

All study-related office visits, medical procedures, laboratory tests, and EFX or placebo will be provided at no cost. Reimbursement for time and travel may also be available.

Find a Participating Research Site

To get involved in this innovative opportunity, contact a participating Symmetry study research site near you:

Long Beach, CA
Digestive Health Research of Southern California
3833 Worsham Avenue
Suite 300
Long Beach, CA 90808
(562) 542-1627
South Bend, IN
Digestive Research Alliance of Michiana
53830 Generations Drive
Suite 110
South Bend, IN 46635
(574) 393-9755
Greenwood, SC
Digestive Disease Research Center
316 West Alexander Avenue
Greenwood, SC 29646
(864) 867-1679

About Clinical Research

Every day, clinical research uncovers new information about medical conditions and their treatment.

Volunteer involvement in research is key to the development and advancement of future therapies. Results collected from clinical studies have led to thousands of medications and devices becoming available to patients all over the world.

As a research participant, you will receive close care and monitoring from specialized medical professionals. Your participation may help advance the research of new, alternative, or better treatments for NASH.

Contact Us

If you have any questions, don’t hesitate to contact us.

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